1 thought on “The intestinal flora controls the five basic elements of human survival”
Beulah
A healthy and diverse intestinal flora is not only inhibiting pathogenic bacteria and helping us break down food. It is also a command center for human health. Almost all health and diseases start in the intestinal tract. Only when we take care of our intestinal and intestinal flora can we take care of us well. It to define the overall health of human beings, there should be five basic elements -immunity, metabolism, hormone balance, cognition and gene expression, which covers all the foundations we need to survive in human beings, and the intestinal flora is the infrastructure, and the intestinal flora Links closely with all these five elements of human health.
immunity Most of us are shocked by human feces bacteria that can cure diseases, Professor David Strachan, an epidemiologist at London Health and Tropical Medical College I won't be surprised by this. In 1989, Professor Strachan observed that babies born in families with more brothers and sisters are not easy to suffer from eczema and allergies, and then propose "hygiene hypothesis". He believes that the less bacteria that children have in early contact, the greater the risk of allergic diseases in the future. Excessive cleaning may be the cause of allergies and autoimmune diseases. This is also the reason for encouraging children to play more soil to improve immunity. In fact, the real problem is not overly clean, but the damage and damage to the healthy intestinal flora. 70%of the human body's immune system is located in the intestine, and they are separated from our intestinal flora through the cell layer with a diameter of only one diameter of the hair, but they are actually closely linked to each other and constantly with each other. communicate with. The intestinal flora helps to promote the normal development of immune cells, identify the invaders, enable immune cells to reach the required position, and then enhance its ability to resist infection. A healthy intestinal flora can be converted into a powerful immune system that allows the immune system to play the best function. When there is a threat, it can quickly identify and eliminate them, including infection or even malignant tumors. We cannot separate the intestinal flora from the immune system. If we hurt one of them, we will hurt the other. The evidence of intestinal-immune-associatedly comes from the epidemic of autoimmune diseases and allergic diseases, and these diseases are erupting around the world. Thenic asthma, allergic rhinitis and eczema are examples of allergic diseases. Among these diseases, the immune system will accidentally attack external stimuli that does not constitute a threat. At the same time, the incidence of autoimmune diseases has continued to soar. Type 1 diabetes, rheumatoid arthritis, multiple sclerosis and Crohn disease are autoimmune diseases. The immune system mistakenly organizes the health of the body as an enemy and launch an attack.
The allergic diseases and autoimmune diseases are more common in industrialized countries than agricultural countries. Everyone may say that this is caused by genetic and racial differences in different regions, but with the improvement of a country's degree of industrialization, these diseases are becoming more and more common within one country. The evidence shows that our intestinal flora will not only change with allergies and autoimmune diseases, but also predict or even cause these immune system diseases. For example, the researchers analyzed the intestinal bacteria of 300 young children, and they found that the specific changes in intestinal bacteria in the early days of life can predict which children will suffer from asthma in a few years. , but in order to prove that the intestinal flora is indeed caused by asthma, the researchers transferred the feces of these children to sterile mice. What needs to be clarified is that these feces are not from patients with asthma, but from a feces bacteria at the age of March at the age of March at the age of children with a risk of asthma. So what happened? The lungs of mice are inflamed, indicating the occurrence of asthma. we have evolved a powerful immune system to protect us from being infected. Our intestinal microorganisms have participated in the evolution process from the beginning, so they play an important role in immune function. This means that the destruction of the intestinal flora will cause us to face the risk of immune dysfunction, manifested as autoimmune diseases and allergic diseases. But on the other hand, a healthy and balanced intestinal flora can give 70%of the best function of immune cells in the intestine to protect us from infection and malignant tumors. Again, when we take good care of our intestinal microorganisms, they will take good care of us.
This metabolism For a long time, we have been told that exercise combined with the correct diet can help us control weight and maintain health. But what if I say that all this is attributed to our intestinal flora? In fact, we have discussed the effects of intestinal flora on weight and health in detail earlier (see: To lose weight and health, first make yourself an excellent "gardener" for intestinal bacteria "gardens"). The report on a septic bacteria also gives us a lot of inspiration. A 32 -year -old young woman accepted the transplantation of fecal bacteria due to chronic causal infections. However, what happened next made scientists and media feel nervous. During her 16 months after her dung transplantation surgery, her weight unexpectedly increased from 61.7 kg to 77 kg. Her height and weight index rose from a very close and healthy weight (BMI 26) To. Everything else in her life has not changed, her diet has not changed, her stress level has not changed, her physical activity level has not changed, but she is transplanted. The results were discovered on animals, which confirmed the important impact of intestinal flora on our weight on humans. Our intestinal flora is greatly controlled by our way of dealing with food and our metabolism process. In fact, the same food can produce completely different effects, depending on our intestinal flora. The study selected the same different ovary twins, but one obese and the other slim. Researchers collected manure samples from the twins and transplanted them into sterile mice. The result was very interesting. Mice who obtained a slim twin feces maintained a slim state, and mice who obtained obese twins became fat. Essence Although these two groups of mice were fed with exactly the same food and exactly the same calories, the body shape was completely different. we have many people spend a lot of time and energy to work hard to lose weight. Now we understand why this may not work for some people, and we need the help of intestinal bacterial partners. We can give two different people to two different people. The differences between their intestinal flora will determine what they eventually get from the food. but it is not only there. Our intestinal flora is not just to regulate our metabolism from the perspective of calorie intake and calorie consumption. It is also closely linked to our endocrine system, affecting our insulin reaction.
. After the meal, our blood glucose level will rise, and the cells in the pancreas will reduce our blood glucose level by releasing insulin to the blood. If you have diabetes, you may not have enough insulin supply to control your blood sugar. 1 Diabetes is an autoimmune disease. The immune system accidentally attacks the pancreatic and pancreatic β cells that produce insulin, which is related to our intestinal health. On the other hand, the pancreatic function of patients with type 2 diabetes is completely normal, and some patients even produce too much insulin. This is the result of insulin resistance, which means that more insulin can be achieved to achieve the same effect. This bacteria will adjust our response to food differently, which will affect the weight gain. So, does intestinal bacteria affect our body's response to insulin? A very interesting study found that adult men with metabolic syndrome and insulin resistance accepted the transplantation of fecal bacteria from a normal supply body, which led to changes in their intestinal flora and thereby Improve insulin sensitivity and reduce blood sugar. Unfortunately, this effect lasted only a few weeks because they did not change their diet, so the new intestinal flora could not be maintained. , but we do not need to have diabetes to show the effects of the intestinal flora. In another study, the researchers found that the same food responded very differently to everyone's blood sugar, and the intestinal flora played an important role in it. Based on a person's intestinal flora, you can predict which food will reduce blood sugar soaring. Everyone's situation is different. In other words, each of us will have a unique response to the food we eat. The loss of the diversity of intestinal bacteria, the increase of the pathogenic bacteria and the chronic low -level inflammation caused by the internal toxins of the bacteria are all related to diabetes, weight gain and obesity. Our intestinal microorganisms also control the release of hormones that regulate appetite and energy balance, such as leptin, stomach hungry, pancreatic hyperglycemic peptide-1 (GLP-1) and peptide YY. Increasing the diversity of intestinal microorganisms is equivalent to improving metabolic health and insulin sensitivity. So when we properly nourish our intestinal flora, as a reward, intestinal microorganisms will help us get everything we need from food, instead of ingesting those things we do not need, intestinal microorganisms It will also tell us when to stop eating so that we will not eat too much. The intestinal microorganisms will also promote the natural balance of metabolism. We do not need to calculate the calories to maintain healthy weight. A healthy intestinal flora can be achieved effortlessly.
The hormone balance The effects of intestinal flora on endocrine or hormone systems are far more than diabetes. The intestine is the largest endocrine organs of the human body, which is deeply involved in ensuring hormone balance. In estrogen as an example, intestinal microorganisms will secrete β-glucosalinase to activate estrogen and make it play its due role in the whole body. If we imagine the flow of estrogen as a river stopped by a dam, and the intestinal microorganisms hold the leverage of the dam gates. When the work is good, the estrogen will remain at the health level. It is not too many nor too small. It provides us with strong bones, healthy cholesterol levels, beautiful skin, healthy ovarian and strong sexual desire. Essence A healthy intestinal flora can help us do this. , but if the intestinal microorganisms are too relaxed, what will happen? The body is full of excess estrogen, which is related to endometriosis, endometrial hyperplasia, breast cancer, and endometrial cancer. It is not surprising that the destruction of intestinal flora is related to these diseases. Instead, if the intestinal microorganisms are limited too much on the gate, it will cause estrogen deficiency. Muctive ovary syndrome is manifested as irregular menstruation, abnormal hair growth, weight gain, acne and insulin resistance. It is a disease characterized by estrogen disorders. The polycystic ovary syndrome is a real hormone imbalance. In addition to the changes in estrogen ,rogen also increases significantly. The facts prove that the production of androgen is also adjusted by intestinal microorganisms to a certain extent. For example, scindens (Scindens) is an intestinal bacteria that can convert glucocorticoids intorogens intorogens in the intestine. So if you have too much cracking bacteria, you will produce too much androgen. The healthy intestinal flora keeps our estrogen androgen to maintain a balance, and the intestinal flora disorders have been found to be related to the polycystic ovary syndrome. The connection between intestinal flora and men's reproductive health. The destruction of the intestinal flora can cause increased intestinal permeability and leave the bacterial internal toxins from the intestine. It may enter the testicles through blood circulation, which causes severe damage, leading to a decline in testicular hormones and sperm. , but the connection between intestinal health and hormones is not stopped. Everyone has some special smells. When men and women are dating, they may be interested in the smell of the dating object, or they may be disgusted. Animal experiments have proved that bacteria can control the release of pinol and other phenolic compounds, and these compounds determine the smell on our body. These are actually pheromone that plays a role in sexual attraction and mating behavior. In other words, our intestinal microorganisms may actually become our matchmaker. Different microorganisms usually release different odor molecules. Healthy microorganisms will emit a pleasant fragrance, while the pathogenic bacteria will release a dislike, keeping people a distance from it. Not every microorganism can be a good helper.
cognitive ability The brain and intestine, one above and one below, most people think that these two organs are two completely independent entities, and the brain is the brain is the brain. Our command center, and the intestine is a bowel movement. Obviously, everyone thinks the brain is the most important. But recently, the dividing line between the brain and the intestine seems to have become a bit blurred, because research found that the intestine has a set of independent nervous system, known as the "intestinal nervous system" or "second brain". In fact, our brain health also begins with the intestine, and they are constantly communicating with each other. Every second, there are more than 500 million nerves in our intestines and send feedback to our brain through the vagus nerves. This is five times more than the nerves we found in the spinal cord. This is just the beginning. The intestinal microorganisms can communicate with our brain through the immune system and the release of neurotransmitters, hormones and signal molecules. Intestinal microorganisms can produce a variety of neurosroofs, including 5-hydroxyline, dopamine, γ-aminocyl acid, and tormeal adrenaline. They play a strong role in our emotions and energy levels. In fact, 90%of 5-hydroxylin and 50%dopamine are generated in our intestine. For example, 5-hydroxylin produced by the intestine can affect intestinal movement, emotion, appetite, sleep and brain function. Our intestine will produce more than thirty types of nerve transmission. The influence of healthy intestinal flora can pass through our blood and brain barrier, helping to maintain our thinking agile, energetic, and relaxing. On the contrary, the destruction of intestinal flora is related to depression, anxiety, Alzheimer's disease, Parkinson disease, migraine, chronic fatigue, autism, and polymorphic disease. The intestine is the base of these neurotransmitters. We can see that when there is a problem with the intestinal tract, the mental health problems such as depression and anxiety usually appear. For example, there are many overlapping between the intestinal syndrome and depression and anxiety. Patients with exciting intestinal syndrome usually show depression and anxiety. However, for a long time, the root cause of the violent fluctuations of emotional fluctuations such as their anxiety or depression may be gastrointestinal problems. Now we know that when our intestinal bacteria change or damage, our 5-hydroxylidine balance will also change, thereby changing emotions and intestinal movements. The end result is anxiety in patients with intestinal syndrome. In fact, the function of 500 million intestinal nerves in the intestinal syndrome has also changed. This is what we call "internal organs feel allergic", which means that they will cause intestinal discomfort, nausea or abdominal pain in some trigger factors that most people can't pay attention to. . Our behavior is also affected by the intestine. There is evidence that the intestinal microorganisms control our appetite. Do you sometimes want to eat something? In fact, it is your intestinal flora talking to you. In fact, intestinal microorganisms may put their interests above us by manipulating our diet. Some of these microorganisms want us to eat sugar, which is harmful to us, but it is beneficial to them. They will improve their health at the cost of sacrificing our health. It remember, we can choose our food, and these options will finally determine our intestinal flora and overall health. More importantly, our desire for food can be changed. We can train our intestinal bacteria to fall in love with those foods that are good for us.
gene expression since Professor James Watson and Francis Crick described the DNA structure in 1953, people seem to have mastered understanding of human health and diseases. key. Nearly 50 years later, after a large -scale international cooperation of 1,000 scientists from 20 institutions, the drawing of sketches of human genome was basically completed in 2000, and the human genetic password was first cracked. we once expect to open a person's genome map, and we can predict a person's life and death, but unfortunately, the higher the expectations, the greater the disappointment, the incredible disappointment of this breakthrough. Since the transliteration of human genetic passwords in 2000, we have not solved all medical problems. Why can't the gene itself help us? Through research on the twins of the ovulation, less than 20%of the disease is caused by genes. For example, cystic fibrosis and Tang family syndrome, if you have those genes, you will get this disease. But looking at all chronic diseases, more than 80%of the risk of illness is determined by our living environment. Therefore, genes do not determine our destiny. Each of us may have some diseases, but our health fate is finally in our hands. Method on the influence of our intestinal flora. This people's own genome is not enough to understand human biology, because there are more than 1,000 microorganisms living in us, and they also seriously affect human life. The number of microorganisms carried by the human body far exceeds the number of cells themselves. The genes encoded by these microorganisms far exceed the genes of human beings. We have more than 99%of the DNA from microorganisms. To 1%. In fact, our own genomes are as high as 99.9%of different individuals, but the microbial genome between people may be as many as 90%of the different. Our intestinal microorganisms can also affect our gene expression through a way called epigenetic inheritance. We can imagine the intestinal flora as a switch that controls the electric lamp, and the wire behind the wall is our genetic password. The intestinal flora does not change the wire behind the wall, but it can control the turning or turned off of the electric light. In other words, we cannot change our genetic passwords, but which genes can affect which genes are opened or closed. The example of epigenetic genetics is cherry diarrhea. Cylinial is a case that the immune system is incorrectly considered to be an attack on foreignic invaders. Gluten is a protein found in wheat, barley and rye. Each of patients with ciliac diarrhea intake, the immune system will attack their intestine, causing inflammation, manifested as diarrhea, weight loss and abdominal pain. This is very dangerous, because patients with cervical diarrhea will develop into small intestinal lymphoma if they continue to intake gluten, which is almost deadly. Tra cervical diarrhea also requires gene participation, which means that you must carry genes that cause cervical diarrhea. If you do not have this gene, you will not get this disease. However, many of us carry the cervical diarrhea, and only a small number of people will show this disease. In the past 50 years, the incidence of cerxar has soared rapidly. So how to explain? is obvious. In that short period of time, our genes have not changed significantly, so what factors will ultimately determine who genes will express? A series of strong studies show that there are three conditions for the occurrence of cervical diarrhea: the first is the existence of susceptible genes, the second is to contact gluten, and the third is the change or destruction of the intestinal flora. In fact, most of the occurrence of autoimmune diseases are the case. (See: The culprit of autoimmune diseases: genetic susceptibility, environmental inducement, and intestinal leakage) Is we think cracking human genome will have a major breakthrough in medicine. This is because we think human health is mainly composed of genes. decided. But in fact, we are a superborn. Our genetic composition is mainly led by the microorganisms that we cannot see in our body. This is actually a good thing for us. Instead of worrying about the less than 1%DNA we can't control, it is better to optimize our intestinal flora through diet and lifestyle to enjoy its more than 99%of the DNA in our body And the positive influence of apparent genetic expression.
The bacteria that were once considered "seeing one" are not so terrible. Our intestine is also a bacterial home. We are harmless and the key to our health. Modern science has clearly told us that most modern diseases are related to the destruction of intestinal flora. The intestinal flora is the engine that drives human health, which affects the five aspects that humans live. The destruction of the intestinal flora can make us sick, and we can also use the intestinal flora to benefit us. The balance of the intestinal flora is very important. Instead of trying to eliminate the sterilization, let us work together, and give us good bacteria through a healthy diet and lifestyle. Bacterial partners can naturally enhance our immune system, metabolism, hormone balance, cognitive ability and gene expression, allowing us to restore health and vitality.
A healthy and diverse intestinal flora is not only inhibiting pathogenic bacteria and helping us break down food. It is also a command center for human health. Almost all health and diseases start in the intestinal tract. Only when we take care of our intestinal and intestinal flora can we take care of us well.
It to define the overall health of human beings, there should be five basic elements -immunity, metabolism, hormone balance, cognition and gene expression, which covers all the foundations we need to survive in human beings, and the intestinal flora is the infrastructure, and the intestinal flora Links closely with all these five elements of human health.
immunity
Most of us are shocked by human feces bacteria that can cure diseases, Professor David Strachan, an epidemiologist at London Health and Tropical Medical College I won't be surprised by this. In 1989, Professor Strachan observed that babies born in families with more brothers and sisters are not easy to suffer from eczema and allergies, and then propose "hygiene hypothesis". He believes that the less bacteria that children have in early contact, the greater the risk of allergic diseases in the future. Excessive cleaning may be the cause of allergies and autoimmune diseases. This is also the reason for encouraging children to play more soil to improve immunity.
In fact, the real problem is not overly clean, but the damage and damage to the healthy intestinal flora. 70%of the human body's immune system is located in the intestine, and they are separated from our intestinal flora through the cell layer with a diameter of only one diameter of the hair, but they are actually closely linked to each other and constantly with each other. communicate with.
The intestinal flora helps to promote the normal development of immune cells, identify the invaders, enable immune cells to reach the required position, and then enhance its ability to resist infection. A healthy intestinal flora can be converted into a powerful immune system that allows the immune system to play the best function. When there is a threat, it can quickly identify and eliminate them, including infection or even malignant tumors. We cannot separate the intestinal flora from the immune system. If we hurt one of them, we will hurt the other.
The evidence of intestinal-immune-associatedly comes from the epidemic of autoimmune diseases and allergic diseases, and these diseases are erupting around the world.
Thenic asthma, allergic rhinitis and eczema are examples of allergic diseases. Among these diseases, the immune system will accidentally attack external stimuli that does not constitute a threat.
At the same time, the incidence of autoimmune diseases has continued to soar. Type 1 diabetes, rheumatoid arthritis, multiple sclerosis and Crohn disease are autoimmune diseases. The immune system mistakenly organizes the health of the body as an enemy and launch an attack.
The allergic diseases and autoimmune diseases are more common in industrialized countries than agricultural countries. Everyone may say that this is caused by genetic and racial differences in different regions, but with the improvement of a country's degree of industrialization, these diseases are becoming more and more common within one country.
The evidence shows that our intestinal flora will not only change with allergies and autoimmune diseases, but also predict or even cause these immune system diseases. For example, the researchers analyzed the intestinal bacteria of 300 young children, and they found that the specific changes in intestinal bacteria in the early days of life can predict which children will suffer from asthma in a few years.
, but in order to prove that the intestinal flora is indeed caused by asthma, the researchers transferred the feces of these children to sterile mice. What needs to be clarified is that these feces are not from patients with asthma, but from a feces bacteria at the age of March at the age of March at the age of children with a risk of asthma. So what happened? The lungs of mice are inflamed, indicating the occurrence of asthma.
we have evolved a powerful immune system to protect us from being infected. Our intestinal microorganisms have participated in the evolution process from the beginning, so they play an important role in immune function. This means that the destruction of the intestinal flora will cause us to face the risk of immune dysfunction, manifested as autoimmune diseases and allergic diseases.
But on the other hand, a healthy and balanced intestinal flora can give 70%of the best function of immune cells in the intestine to protect us from infection and malignant tumors. Again, when we take good care of our intestinal microorganisms, they will take good care of us.
This metabolism
For a long time, we have been told that exercise combined with the correct diet can help us control weight and maintain health. But what if I say that all this is attributed to our intestinal flora? In fact, we have discussed the effects of intestinal flora on weight and health in detail earlier (see: To lose weight and health, first make yourself an excellent "gardener" for intestinal bacteria "gardens").
The report on a septic bacteria also gives us a lot of inspiration. A 32 -year -old young woman accepted the transplantation of fecal bacteria due to chronic causal infections. However, what happened next made scientists and media feel nervous. During her 16 months after her dung transplantation surgery, her weight unexpectedly increased from 61.7 kg to 77 kg. Her height and weight index rose from a very close and healthy weight (BMI 26) To. Everything else in her life has not changed, her diet has not changed, her stress level has not changed, her physical activity level has not changed, but she is transplanted.
The results were discovered on animals, which confirmed the important impact of intestinal flora on our weight on humans. Our intestinal flora is greatly controlled by our way of dealing with food and our metabolism process. In fact, the same food can produce completely different effects, depending on our intestinal flora.
The study selected the same different ovary twins, but one obese and the other slim. Researchers collected manure samples from the twins and transplanted them into sterile mice. The result was very interesting. Mice who obtained a slim twin feces maintained a slim state, and mice who obtained obese twins became fat. Essence Although these two groups of mice were fed with exactly the same food and exactly the same calories, the body shape was completely different.
we have many people spend a lot of time and energy to work hard to lose weight. Now we understand why this may not work for some people, and we need the help of intestinal bacterial partners. We can give two different people to two different people. The differences between their intestinal flora will determine what they eventually get from the food.
but it is not only there. Our intestinal flora is not just to regulate our metabolism from the perspective of calorie intake and calorie consumption. It is also closely linked to our endocrine system, affecting our insulin reaction.
. After the meal, our blood glucose level will rise, and the cells in the pancreas will reduce our blood glucose level by releasing insulin to the blood. If you have diabetes, you may not have enough insulin supply to control your blood sugar.
1 Diabetes is an autoimmune disease. The immune system accidentally attacks the pancreatic and pancreatic β cells that produce insulin, which is related to our intestinal health. On the other hand, the pancreatic function of patients with type 2 diabetes is completely normal, and some patients even produce too much insulin. This is the result of insulin resistance, which means that more insulin can be achieved to achieve the same effect.
This bacteria will adjust our response to food differently, which will affect the weight gain. So, does intestinal bacteria affect our body's response to insulin?
A very interesting study found that adult men with metabolic syndrome and insulin resistance accepted the transplantation of fecal bacteria from a normal supply body, which led to changes in their intestinal flora and thereby Improve insulin sensitivity and reduce blood sugar. Unfortunately, this effect lasted only a few weeks because they did not change their diet, so the new intestinal flora could not be maintained.
, but we do not need to have diabetes to show the effects of the intestinal flora. In another study, the researchers found that the same food responded very differently to everyone's blood sugar, and the intestinal flora played an important role in it. Based on a person's intestinal flora, you can predict which food will reduce blood sugar soaring. Everyone's situation is different. In other words, each of us will have a unique response to the food we eat.
The loss of the diversity of intestinal bacteria, the increase of the pathogenic bacteria and the chronic low -level inflammation caused by the internal toxins of the bacteria are all related to diabetes, weight gain and obesity. Our intestinal microorganisms also control the release of hormones that regulate appetite and energy balance, such as leptin, stomach hungry, pancreatic hyperglycemic peptide-1 (GLP-1) and peptide YY. Increasing the diversity of intestinal microorganisms is equivalent to improving metabolic health and insulin sensitivity.
So when we properly nourish our intestinal flora, as a reward, intestinal microorganisms will help us get everything we need from food, instead of ingesting those things we do not need, intestinal microorganisms It will also tell us when to stop eating so that we will not eat too much. The intestinal microorganisms will also promote the natural balance of metabolism. We do not need to calculate the calories to maintain healthy weight. A healthy intestinal flora can be achieved effortlessly.
The hormone balance
The effects of intestinal flora on endocrine or hormone systems are far more than diabetes. The intestine is the largest endocrine organs of the human body, which is deeply involved in ensuring hormone balance.
In estrogen as an example, intestinal microorganisms will secrete β-glucosalinase to activate estrogen and make it play its due role in the whole body. If we imagine the flow of estrogen as a river stopped by a dam, and the intestinal microorganisms hold the leverage of the dam gates.
When the work is good, the estrogen will remain at the health level. It is not too many nor too small. It provides us with strong bones, healthy cholesterol levels, beautiful skin, healthy ovarian and strong sexual desire. Essence A healthy intestinal flora can help us do this.
, but if the intestinal microorganisms are too relaxed, what will happen? The body is full of excess estrogen, which is related to endometriosis, endometrial hyperplasia, breast cancer, and endometrial cancer. It is not surprising that the destruction of intestinal flora is related to these diseases. Instead, if the intestinal microorganisms are limited too much on the gate, it will cause estrogen deficiency.
Muctive ovary syndrome is manifested as irregular menstruation, abnormal hair growth, weight gain, acne and insulin resistance. It is a disease characterized by estrogen disorders. The polycystic ovary syndrome is a real hormone imbalance. In addition to the changes in estrogen ,rogen also increases significantly.
The facts prove that the production of androgen is also adjusted by intestinal microorganisms to a certain extent. For example, scindens (Scindens) is an intestinal bacteria that can convert glucocorticoids intorogens intorogens in the intestine. So if you have too much cracking bacteria, you will produce too much androgen. The healthy intestinal flora keeps our estrogen androgen to maintain a balance, and the intestinal flora disorders have been found to be related to the polycystic ovary syndrome.
The connection between intestinal flora and men's reproductive health. The destruction of the intestinal flora can cause increased intestinal permeability and leave the bacterial internal toxins from the intestine. It may enter the testicles through blood circulation, which causes severe damage, leading to a decline in testicular hormones and sperm.
, but the connection between intestinal health and hormones is not stopped. Everyone has some special smells. When men and women are dating, they may be interested in the smell of the dating object, or they may be disgusted. Animal experiments have proved that bacteria can control the release of pinol and other phenolic compounds, and these compounds determine the smell on our body. These are actually pheromone that plays a role in sexual attraction and mating behavior. In other words, our intestinal microorganisms may actually become our matchmaker. Different microorganisms usually release different odor molecules. Healthy microorganisms will emit a pleasant fragrance, while the pathogenic bacteria will release a dislike, keeping people a distance from it. Not every microorganism can be a good helper.
cognitive ability
The brain and intestine, one above and one below, most people think that these two organs are two completely independent entities, and the brain is the brain is the brain. Our command center, and the intestine is a bowel movement. Obviously, everyone thinks the brain is the most important. But recently, the dividing line between the brain and the intestine seems to have become a bit blurred, because research found that the intestine has a set of independent nervous system, known as the "intestinal nervous system" or "second brain".
In fact, our brain health also begins with the intestine, and they are constantly communicating with each other. Every second, there are more than 500 million nerves in our intestines and send feedback to our brain through the vagus nerves. This is five times more than the nerves we found in the spinal cord.
This is just the beginning. The intestinal microorganisms can communicate with our brain through the immune system and the release of neurotransmitters, hormones and signal molecules. Intestinal microorganisms can produce a variety of neurosroofs, including 5-hydroxyline, dopamine, γ-aminocyl acid, and tormeal adrenaline. They play a strong role in our emotions and energy levels.
In fact, 90%of 5-hydroxylin and 50%dopamine are generated in our intestine. For example, 5-hydroxylin produced by the intestine can affect intestinal movement, emotion, appetite, sleep and brain function. Our intestine will produce more than thirty types of nerve transmission.
The influence of healthy intestinal flora can pass through our blood and brain barrier, helping to maintain our thinking agile, energetic, and relaxing. On the contrary, the destruction of intestinal flora is related to depression, anxiety, Alzheimer's disease, Parkinson disease, migraine, chronic fatigue, autism, and polymorphic disease.
The intestine is the base of these neurotransmitters. We can see that when there is a problem with the intestinal tract, the mental health problems such as depression and anxiety usually appear. For example, there are many overlapping between the intestinal syndrome and depression and anxiety. Patients with exciting intestinal syndrome usually show depression and anxiety. However, for a long time, the root cause of the violent fluctuations of emotional fluctuations such as their anxiety or depression may be gastrointestinal problems. Now we know that when our intestinal bacteria change or damage, our 5-hydroxylidine balance will also change, thereby changing emotions and intestinal movements. The end result is anxiety in patients with intestinal syndrome.
In fact, the function of 500 million intestinal nerves in the intestinal syndrome has also changed. This is what we call "internal organs feel allergic", which means that they will cause intestinal discomfort, nausea or abdominal pain in some trigger factors that most people can't pay attention to.
. Our behavior is also affected by the intestine. There is evidence that the intestinal microorganisms control our appetite. Do you sometimes want to eat something? In fact, it is your intestinal flora talking to you. In fact, intestinal microorganisms may put their interests above us by manipulating our diet. Some of these microorganisms want us to eat sugar, which is harmful to us, but it is beneficial to them. They will improve their health at the cost of sacrificing our health.
It remember, we can choose our food, and these options will finally determine our intestinal flora and overall health. More importantly, our desire for food can be changed. We can train our intestinal bacteria to fall in love with those foods that are good for us.
gene expression
since Professor James Watson and Francis Crick described the DNA structure in 1953, people seem to have mastered understanding of human health and diseases. key. Nearly 50 years later, after a large -scale international cooperation of 1,000 scientists from 20 institutions, the drawing of sketches of human genome was basically completed in 2000, and the human genetic password was first cracked.
we once expect to open a person's genome map, and we can predict a person's life and death, but unfortunately, the higher the expectations, the greater the disappointment, the incredible disappointment of this breakthrough. Since the transliteration of human genetic passwords in 2000, we have not solved all medical problems.
Why can't the gene itself help us? Through research on the twins of the ovulation, less than 20%of the disease is caused by genes. For example, cystic fibrosis and Tang family syndrome, if you have those genes, you will get this disease. But looking at all chronic diseases, more than 80%of the risk of illness is determined by our living environment.
Therefore, genes do not determine our destiny. Each of us may have some diseases, but our health fate is finally in our hands. Method on the influence of our intestinal flora.
This people's own genome is not enough to understand human biology, because there are more than 1,000 microorganisms living in us, and they also seriously affect human life. The number of microorganisms carried by the human body far exceeds the number of cells themselves. The genes encoded by these microorganisms far exceed the genes of human beings. We have more than 99%of the DNA from microorganisms. To 1%. In fact, our own genomes are as high as 99.9%of different individuals, but the microbial genome between people may be as many as 90%of the different.
Our intestinal microorganisms can also affect our gene expression through a way called epigenetic inheritance. We can imagine the intestinal flora as a switch that controls the electric lamp, and the wire behind the wall is our genetic password. The intestinal flora does not change the wire behind the wall, but it can control the turning or turned off of the electric light. In other words, we cannot change our genetic passwords, but which genes can affect which genes are opened or closed.
The example of epigenetic genetics is cherry diarrhea. Cylinial is a case that the immune system is incorrectly considered to be an attack on foreignic invaders. Gluten is a protein found in wheat, barley and rye. Each of patients with ciliac diarrhea intake, the immune system will attack their intestine, causing inflammation, manifested as diarrhea, weight loss and abdominal pain. This is very dangerous, because patients with cervical diarrhea will develop into small intestinal lymphoma if they continue to intake gluten, which is almost deadly.
Tra cervical diarrhea also requires gene participation, which means that you must carry genes that cause cervical diarrhea. If you do not have this gene, you will not get this disease. However, many of us carry the cervical diarrhea, and only a small number of people will show this disease. In the past 50 years, the incidence of cerxar has soared rapidly. So how to explain?
is obvious. In that short period of time, our genes have not changed significantly, so what factors will ultimately determine who genes will express? A series of strong studies show that there are three conditions for the occurrence of cervical diarrhea: the first is the existence of susceptible genes, the second is to contact gluten, and the third is the change or destruction of the intestinal flora. In fact, most of the occurrence of autoimmune diseases are the case. (See: The culprit of autoimmune diseases: genetic susceptibility, environmental inducement, and intestinal leakage)
Is we think cracking human genome will have a major breakthrough in medicine. This is because we think human health is mainly composed of genes. decided. But in fact, we are a superborn. Our genetic composition is mainly led by the microorganisms that we cannot see in our body. This is actually a good thing for us. Instead of worrying about the less than 1%DNA we can't control, it is better to optimize our intestinal flora through diet and lifestyle to enjoy its more than 99%of the DNA in our body And the positive influence of apparent genetic expression.
The bacteria that were once considered "seeing one" are not so terrible. Our intestine is also a bacterial home. We are harmless and the key to our health. Modern science has clearly told us that most modern diseases are related to the destruction of intestinal flora.
The intestinal flora is the engine that drives human health, which affects the five aspects that humans live. The destruction of the intestinal flora can make us sick, and we can also use the intestinal flora to benefit us. The balance of the intestinal flora is very important. Instead of trying to eliminate the sterilization, let us work together, and give us good bacteria through a healthy diet and lifestyle. Bacterial partners can naturally enhance our immune system, metabolism, hormone balance, cognitive ability and gene expression, allowing us to restore health and vitality.